Categories: Endocrinology

7 I’s of DKA: Causes Mnemonic

When a patient presents with DKA, it is important to try to elucidate the cause. An easy way to remember those causes are the 7 I’s of DKA:

  1. Infection: Look for potential infectious foci (pneumonia, bacteremia, UTI etc.).
  2. Ischemia: Such as ACS, critical limb ischemia or ischemic bowel.
  3. Intoxication: ETOH, MDMA, Cocaine, Methamphetamine etc. 
  4. Infraction/ Intolerance: Patient not taking their insulin. 
  5. Iatrogenic: Secondary to medications (i.e steroids) or surgeries.
  6. Initial Presentation: First time presentation typically in young children. 
  7. Impregnation: Increased metabolic demands of pregnancy make precipitate an episode of DKA.

*NOTE: These causes are also precipitants for Hyperosmolar Hyperglycemic State (HHS).

REFERENCES

  1. Umpierrez GE, Kitabchi AE. Diabetic ketoacidosis: risk factors and management strategies. Treat Endocrinol. 2003;2(2):95-108.
Get Medical Pearls directly to your inbox every week!
Weekly posts with high yield medical knowledge, directly to your mailbox!
Dr. C Humphreys

Internal Medicine

Recent Posts

What is Peribronchovascular Distribution on CT imaging?

A common finding described on computed tomography (CT) imaging. A disease with a peribronchovascular distribution…

2 months ago

Trapped Lung vs. Lung Entrapment

Though often used synonymously; Trapped Lung and Lung Entrapment technically describe separate entities along the…

8 months ago

Cause of Pericardial Effusion in Pulmonary Hypertension: Pathogenesis

It is not clearly understood why patients with pulmonary hypertension (PH) develop pericardial effusions. However,…

9 months ago

Difference between Mycophenolate Mofetil vs. Mycophenolate Sodium

The two drugs are not interchangeable nor dose equivalents. Mycophenolate mofetil (Cellcept) is a semi…

10 months ago

What is an “Anephric” Creatinine Rise?

Serum Creatinine can be a deceptive surrogate during an acute kidney injury. It may lag…

2 years ago

Macrophage activation syndrome vs. Hemophagocytic lymphohistiocytosis

Macrophage activation syndrome (MAS) is a life-threatening complication of rheumatic diseases (i.e SLE, Juvenile idiopathic…

2 years ago

This website uses cookies.