Dihydropyridine: Think Amlodipine and Nifedipine (-dipine)
They act through systemic vascular vasodilation of arteries. Can be used to treat angina. NOTE: can cause hypotension and cause reflex tachycardia (this is bad for patients with ischemic symptoms)
Non-Dihydropyridine: Think Verapamil and Diltiazem
They act selectively on the myocardium. This will reduce oxygen demand of myocardial tissue. They have minimal systemic effect and are less likely to cause reflex tachycardia.
REFERENCES
1. Hockerman, G.H.; Peterson, B.Z.; Johnson, B.D.; Catterall, W.A. (1997). “Molecular Determinants of Drug Binding and Action on L-Type Calcium Channels”. Annual Review of Pharmacology and Toxicology 37: 361–396
Mixed apneas are characterized by absent respiratory effort and airflow in the first section of…
Although rare, the differential diagnosis of hypoventilation and hypercapnia respiratory failure includes hypothyroidism. It is…
B-type natriuretic peptide (BNP) is a hormone created in response to cardiac wall stretch due…
A common finding described on computed tomography (CT) imaging. A disease with a peribronchovascular distribution…
Though often used synonymously; Trapped Lung and Lung Entrapment technically describe separate entities along the…
It is not clearly understood why patients with pulmonary hypertension (PH) develop pericardial effusions. However,…
This website uses cookies.