On an urine dipstick for suspected UTI, it is not uncommon to find positive nitrites. Nitrates are normally excreted by the kidney, however nitrites are not normally found in urine. Nitrites will be found when nitrate reductase organisms are present in the patient’s urine. These organisms are gram-negative bacteria including E. coli and other bacteria in the family Enterobacteriaceae (i.e Klebsiella).
NOTE: However, several other common urinary pathogens do not produce nitrites, such as: enterococci, S. saprophyticus, and Pseudomonas!! Therefore negative nitrites DOES NOT RULE OUT BACTERIURIA.
WATCH OUT FOR FALSE (-):
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