Categories: Hematology/Oncology

What are the complications of massive Blood Transfusion?

MOST COMMON:

    • FNHTR [Febrile non-hemolytic transfusion reaction] (5% with platelets, <1% with RBCs), allo-immunization to red cell antigen

Serious:

    • TACO [Transfusion associated circulatory overload] 
    • TRALI [Transfusion-related acute lung injury] 
    • Acute hemolytic transfusion reaction
    • Anaphylactic reaction 
    • Hyperkalemia & Hypocalcemia 

Infection:

    • Hepatitis B (1/150,000), Hepatitis C (1/2-3 million), HIV (1/7.8 million)

REFERENCES

  1. Chapter 12. Hematopathology. Pathology: The Big Picture
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Dr. C Humphreys

Internal Medicine

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