Alcoholic hepatitis lab findings classically reveal serum AST/ ALT >2. (Although rarely above 300 IU per milliliter). Although this finding is neither specific nor sensitive.
WHY??? The proposed mechanisms accounting for this high ratio are reduced hepatic alanine aminotransferase activity, alcohol-induced depletion of hepatic pyridoxal 5′-phosphate (B6), and increased hepatic mitochondrial aspartate.
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