Daptomycin (lipopeptide): typically used for VRE and MRSA, but has had poor efficacy in clinical trials for CAP.
Proposed rationale: Daptomycin inserts into the membrane of gram-positive bacteria and artificial lipid vesicles. In the lungs, Daptomycin will insert into the lipid surfactant layer (which is abundant) due to lack of targeted specificity for the anti-microbial pathogens. Hence it will be effectively sequestrated and rendered inactive by pulmonary surfactant.
References
Obstructive sleep apnea (OSA) is thought to lead to secondary polycythemia due to intermittent hypoxia,…
Catabolism of hemoglobin leads to the release of heme, which converts to biliverdin and then…
Tongue scalloping refers to the series of indentations along the sides of the tongue that…
Older age is recognized as a risk factor for obstructive sleep apnea.[1] But why? Suspected…
Being overweight (BMI ≥ 25 kg/m2)/Obese (BMI ≥ 30 kg/m2) is one of the most…
Nocturia is a common symptom associated with obstructive sleep apnea. [1] Img Cred: Am J…
This website uses cookies.