Current serological testing detects the IgA isotype of the Anti-TTG antibodies. Hence if a person is IgA deficient they will lack the prerequisite antibodies for testing despite the possibility of Celiac disease. The IgG class of anti-tTG may be ordered as an alternative in those who have a deficiency of IgA. Approximately 2-3% of the time in people with Celiac disease there is concurrent IgA deficiency and can lead to false-negative test results. [1]
References
1. Rittmeyer, C., Rhoads, J. M. 1996. IgA deficiency causes false-negative endomysial antibody results in celiac disease. J. Pediatr. Gastroenterol. Nutr. 23:504-506.
Nocturia is a common symptom associated with obstructive sleep apnea. [1] Img Cred: Am J…
ASD (Atrial Septal Defect) Wide, Fixed split S2 (in contrast to the normal variation in…
Mixed apneas are characterized by absent respiratory effort and airflow in the first section of…
Although rare, the differential diagnosis of hypoventilation and hypercapnia respiratory failure includes hypothyroidism. It is…
B-type natriuretic peptide (BNP) is a hormone created in response to cardiac wall stretch due…
A common finding described on computed tomography (CT) imaging. A disease with a peribronchovascular distribution…
This website uses cookies.