Categories: Rheumatology

Why does the lupus malar rash spare the nasolabial folds?

Malar rash (also known as the “butterfly rash,”) is an acute manifestation of lupus (SLE) seen in over 50% of patients. It is a bilateral, erythematous maculopapular rash which spares the nasolabial folds. The rash will last anywhere from days to weeks, and it can be painful/ itchy. It is a photosensitivity phenomenon.

Suspected Mechanism: the nasolabial folds are a relatively UV protected surface and therefore less affected.

REFERENCES:

  1. Amre Nouh, Jodi Speiser, José Biller. Chapter 3 – Acquired neurocutaneous disorders. Handbook of Clinical Neurology. Volume 132, 2015, Pages 29-73
  2. Fitzpatrick’s Color Atlas and Synopsis of Clinical Dermatology, 8e. Klaus Wolff, Richard Allen Johnson, Arturo P. Saavedra, Ellen K. Roh. THE SKIN IN IMMUNE, AUTOIMMUNE, AUTOINFLAMMATORY, AND RHEUMATIC DISORDERS.
Get Medical Pearls directly to your inbox every week!
Weekly posts with high yield medical knowledge, directly to your mailbox!
Dr. C Humphreys

Internal Medicine

Recent Posts

Older Age and Obstructive Sleep Apnea (OSA): Mechanism

Older age is recognized as a risk factor for obstructive sleep apnea.[1] But why? Suspected…

2 months ago

How does Weight Affect Obstructive Sleep Apnea (OSA): Mechanism

Being overweight (BMI ≥ 25 kg/m2)/Obese (BMI ≥ 30 kg/m2) is one of the most…

2 months ago

Nocturia and OSA: Mechanism

Nocturia is a common symptom associated with obstructive sleep apnea. [1] Img Cred: Am J…

1 year ago

ASD vs. VSD Murmur Difference

ASD (Atrial Septal Defect) Wide, Fixed split S2 (in contrast to the normal variation in…

1 year ago

Mechanism of a Mixed Apnea

Mixed apneas are characterized by absent respiratory effort and airflow in the first section of…

2 years ago

How Does Hypothyroidism Cause Hypoventilation?

Although rare, the differential diagnosis of hypoventilation and hypercapnia respiratory failure includes hypothyroidism. It is…

2 years ago

This website uses cookies.