- Thiamine 100mg IV before 50% glucose
- Thiamine is an important co-enzyme for carbohydrate utilization as (thiamine pyrophosphate- TPP)
- Therefore TTP is required to convert pyruvate to Acetyl-CoA. To put it another way, if you’re thiamine deficient, any glucose you get will tend to form lactate, rather than being fully metabolized in the Krebs Cycle [1]
References
- Hoyumpa AM, Jr. Mechanisms of thiamin deficiency in chronic alcoholism. Am J Clin Nutr 1980;33:2750-2761.