Categories: Infectious Diseases

Asplenia and Encapsulated Bacteria

Splenectomy may be necessary 2° to: 1) trauma 2) cancer (i.e multiple myeloma, ALL, CLL) 3) ITP refractory to treatment. Certain disease states may result in functional asplenia (i.e Sickle cell disease).

REMEMBER *SHIN* for encapsulated organisms:

Streptococcus pneumoniae

Haemophilus Influenzae

Neisseria meningitidis

NOTE: The risk of sepsis after splenectomy is highest in the first couple of years!


  1. Capnocytophaga canimorsus – Increased risk from cat and dog bites
  2. Babesia microti- Tick precautions when at risk for tick exposure in areas of risk 
  3. Salmonella typhi- Leading cause of Osteomyelitis in Sickle Cell patients


  1. Principles and Practice of Hospital Medicine.  Chapter 198. Infections of the Immunocompromised Host. Sarah P. Hammond, MD; Lindsey R. Baden, MD
  2. 374: Primary Immune Deficiency Diseases. Harrison’s Principles of Internal Medicine, 19. Alain Fischer
Get Medical Pearls directly to your inbox every week!
Weekly posts with high yield medical knowledge, directly to your mailbox!
Dr. C Humphreys

Internal Medicine

Published by
Dr. C Humphreys

Recent Posts

Nocturia and OSA: Mechanism

Nocturia is a common symptom associated with obstructive sleep apnea. [1] Img Cred: Am J…

8 months ago

ASD vs. VSD Murmur Difference

ASD (Atrial Septal Defect) Wide, Fixed split S2 (in contrast to the normal variation in…

8 months ago

Mechanism of a Mixed Apnea

Mixed apneas are characterized by absent respiratory effort and airflow in the first section of…

2 years ago

How Does Hypothyroidism Cause Hypoventilation?

Although rare, the differential diagnosis of hypoventilation and hypercapnia respiratory failure includes hypothyroidism. It is…

2 years ago

Why is Pro-BNP/ BNP lower in Obesity?

B-type natriuretic peptide (BNP) is a hormone created in response to cardiac wall stretch due…

2 years ago

What is Peribronchovascular Distribution on CT imaging?

A common finding described on computed tomography (CT) imaging. A disease with a peribronchovascular distribution…

3 years ago

This website uses cookies.