The two drugs are not interchangeable, nor dose equivalents.
Mycophenolate mofetil (Cellcept) is a semi-synthetic prodrug that is rapidly hydrolyzed in vivo to form the active metabolite, mycophenolic acid (MPA).
Mycophenolate sodium (Myfortic) is an enteric-coated formulation that allows delayed release of MPA into the small intestine.
Myfortic typically causes less diarrhea, indigestion, and abdominal compared to CellCept [1].
REFERENCES:
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