Serum Creatinine can be a deceptive surrogate during an acute kidney injury. It may lag behind acute onset renal failure and misrepresent the current degree of renal impairment.
RULE OF THUMB: During an AKI, a creatinine rise of 1-1.5mg/dL (88.4-132.6umol/L) per day is considered an anephric rise. It is the average expected rise in a person with a GFR of 0mL/minute.
Example: Cr rise of 1mg/dL to 2mg/dL is considered an “anephric rise”.
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