Macrophage activation syndrome (MAS) is a life-threatening complication of rheumatic diseases (i.e SLE, Juvenile idiopathic arthritis, Adult onset Still’s disease). It manifests as uncontrolled activation and proliferation of T lymphocytes and macrophages
Hemophagocytic lymphohistiocytosis (HLH) is an inherited disease, or secondary overactivation of histiocytes and lymphocytes triggered by other diseases, including infections (i.e EBV, HSV, CMV), malignancy (i.e Lymphoma, Leukemia), and autoimmune diseases.
***Both can present with high-grade fever (>39C), hemorrhagic manifestations (DIC), hepatosplenomegaly and lymphadenopathy.
BOTH require immediate and appropriate treatment.
REFERENCES
Mixed apneas are characterized by absent respiratory effort and airflow in the first section of…
Although rare, the differential diagnosis of hypoventilation and hypercapnia respiratory failure includes hypothyroidism. It is…
B-type natriuretic peptide (BNP) is a hormone created in response to cardiac wall stretch due…
A common finding described on computed tomography (CT) imaging. A disease with a peribronchovascular distribution…
Though often used synonymously; Trapped Lung and Lung Entrapment technically describe separate entities along the…
It is not clearly understood why patients with pulmonary hypertension (PH) develop pericardial effusions. However,…
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