Hungry Bone syndrome is a phenomenon of post-operative hypocalcemia. It is an uncommon, but serious post-surgical sequalae of parathyroidectomy.
It is profound and sustained hypocalcaemia (often with concurrent hypomagnesaemia and hypophosphataemia) despite a normal PTH.
The primary patient demography is those with severe primary hyperparathyroidism and preoperative high bone turnover (osteitis fibrosa).
WHY? The severe hypocalcaemia is thought to be secondary to increased influx of calcium into bone, due to the sudden loss of high circulating levels of PTH on chronically elevated osteoclastic resorption.
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