Why does DKA initially get worse when you start treating it?

9 years ago

When you begin to treat DKA, it paradoxically appears to get worse on urinalysis before getting better. WHY? Serum ketones…

When to use FeUrea over FeNa?

9 years ago

When trying to determine the etiology of AKI (pre-renal, renal, post-renal) FeNa is often checked. It would be expected in…

What is the urine anion gap?

9 years ago

Urine AG = Urine (Na + K – Cl) NOTE: In the setting of Bicarbonate loss, kidneys will retain Bicarbonate…

Why does Creatinine Clearance overestimate GFR?

9 years ago

Creatinine is a metabolic byproduct generated from muscle breakdown. Creatinine is filtered from blood by the kidneys and is not…

How does Allopurinol work?

9 years ago

Allopurinol => enzyme xanthine oxidase inhibitor Therefore blocks the conversion of the purine metabolites (hypoxanthine and xanthine) into uric acid.…

What’s the difference between penicillin G and penicillin V (VK)?

9 years ago

Both are first generation penicillins Pencillin G => IV or IM Penicillin V (phenoxymethylpenicillin) => more acidic, more stable and…

Epithelial cells in sputum?

9 years ago

Typically a sputum gram stain will be sent off to isolate potential respiratory pathogens. Normally your findings should contain many…

Why CT before LP in Suspected Meningitis?

9 years ago

Traditional thinking was if there is a space occupying lesion, it may result in increased ICP. When you perform a…

Why & How to Monitor Vancomycin Troughs?

9 years ago

Vancomycin is a glycopeptide antibiotic, typically used for treatment of MRSA. Traditionally it is recommended to get trough doses to…

Why does Tuberculosis tend to reactivate in upper lung lobes?

9 years ago

Mycobacterium tuberculosis is an obligate aerobe and only survives in oxygenated areas. Exact reason for TB's propensity to reactivate in…

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