The serum osmolality is calculated by the concentrations of the different effective osmoles which compose it. The formula:
Calculated Sosm = (2 x serum [Na]) + [glucose] + [urea] (SI)
Calculated Sosm = (2 x serum [Na]) + [glucose, in mg/dL]/18 + [blood urea nitrogen, in mg/dL] (US)
WHY SODIUM TIMES TWO? The serum sodium is multiplied by two in order to account for the negatively charged solutes that must accompany it in the serum to maintain net neutrality in the body (i.e chloride and bicarbonate).
REFERENCES
A common finding described on computed tomography (CT) imaging. A disease with a peribronchovascular distribution…
Though often used synonymously; Trapped Lung and Lung Entrapment technically describe separate entities along the…
It is not clearly understood why patients with pulmonary hypertension (PH) develop pericardial effusions. However,…
The two drugs are not interchangeable nor dose equivalents. Mycophenolate mofetil (Cellcept) is a semi…
Serum Creatinine can be a deceptive surrogate during an acute kidney injury. It may lag…
Macrophage activation syndrome (MAS) is a life-threatening complication of rheumatic diseases (i.e SLE, Juvenile idiopathic…
This website uses cookies.