Hematology/Oncology

Why Urine Dipstick is Negative in Multiple Myeloma?

Urine dipsticks only detect albumin and not all proteins, including light chains (i.e Bence Jones Protein). Therefore, a patient with Multiple Myeloma who has a large amount of light chains in the urine will not have a conventional positive dipstick. [1]

References

1. Dimopoulos M, Kyle R, Fermand JP, Rajkumar SV, San Miguel J, et al. Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3. Blood. 2011 May 5. 117 (18):4701-5.

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Dr. C Humphreys

Internal Medicine

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Dr. C Humphreys

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