Indications for Dialysis in Acute Kidney Injury (AKI)

8 years ago

1. Refractory Fluid Overload 2. Severe hyperkalemia (>6.5 mEq/L) or rapidly rising potassium levels 3. Signs of uremia including pericarditis,…

Proton Pump Inhibitors for Upper GI Bleed: Mechanism

8 years ago

During the bleed, there will be sympathetic mediated vasoconstriction and also hemostasis (platelet plug). It has been demonstrated in an…

Lactated Ringer’s (LR)

8 years ago

Isotonic pH 6.6 130 mEq Sodium 4 mEq Potassium 3 mEq Calcium 109 mEq Chloride 28 mEq Sodium Lactate (provides…

Pulmonary Embolism causing Obstructive Shock: Mechanism

8 years ago

Obstructive shock occurs due to obstruction of the cardiovascular system. Commonly due to PE, Tension pneumothorax and Tamponade. HOW? PE…

Hypercalcemia in Granulomatous Disorders: Mechanism

8 years ago

Hypercalcemia can occur in the context of several granulomatous diseases including: Sarcoidosis, Wegener’s granulomatosis, Silicosis, Berylliosis, Tuberculosis, Fungal granulomas and…

Why does Dumping Syndrome cause Hypoglycemia?

8 years ago

The stomach acts as a reservoir for digestion. Food will be stored and broken down in it via acid and…

What is Fat Stranding?

8 years ago

Fat stranding is a term used to describe increased (abnormal) attenuation of fat on CT scan typically. It is suggestive…

Why does Iron Poisoning cause Metabolic Acidosis?

8 years ago

Iron poisoning is often listed in the classic metabolic acidosis mnemonic MUDPILES, but how does it cause an anion gap…

MGUS vs. Multiple Myeloma vs. Waldenstrom’s

8 years ago

Monoclonal gammopathy of undetermined significance (MGUS) Asymptomatic premalignant state Common in elderly population (~10% in patients >75 years old) Paraprotein…

pRBCs: Hypotonic solution vs. Ringer Lactate

8 years ago

Do not mix pRBC infusion with hypotonic solution (i.e D5W). Why? The hypotonic solution has a lower osmolarity, will shift…

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