Vancomycin-resistant enterococci (VRE) first appeared in Europe during the 1980s. It rapidly spread to North America by the 1990s. 

Susceptibility:

More than 50% of E. faecium in the United States are VRE.

E. faecalis tends to be susceptible to vancomycin.

Most frequent form of VRE infection: UTI, followed by catheter line associated bacteremia (i.e hemodialysis, central lines).

Treatment for VRE: daptomycin, linezolid, and tigecycline. Susceptible strains may be treated with ampicillin.

REFERENCES:

  1. Principles and Practice of Hospital Medicine, 2e. Chapter 185: Antibiotic Resistance. L. Silvia Munoz-Price.

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