Endocrinology

Pheochromocytoma: Why Alpha and Beta Blockers?

Pheochromocytoma= A rare catecholamine producing tumour that originate from chromaffin cells in the adrenal medulla. Patients classically present with: paroxysmal…

9 years ago

Causes of Pancreatitis: I GET SMASHED

Idiopathic (i.e microlithiasis) ·         Gallstones Endoscopic retrograde cholangiopancreatography (ERCP)         Trauma (especially blunt abdominal trauma)·   Scorpion bites (Tityus trinitatis, Trinidad) Mumps.…

9 years ago

Signs of Hypocalcemia

HYPOCALCEMIA Low serum calcium levels in the blood< 2.12mmol/L (TOTAL) and <1.16mmol/L (+) Signs and Symptoms POSITIVE bathmotropic effects due…

9 years ago

Why does Hyperglycemia cause Hyponatremia?

The human body will maintain a serum [Na+] between 135 and 145 mEq/L. Hyponatremia in the context of hypergylcemia is…

9 years ago

Why does Addison disease cause hyperpigmented skin?

 Addison disease => autoimmune destruction of adrenal glands The destruction results in less cortisol production by adrenals. This causes an…

9 years ago

Fruity Breath in DKA: Mechanism

Acetone produces the characteristic fruity odor on the breath found in some patients in DKA. HOW? Acetone is very volatile…

10 years ago

Serum vs. Total Body Potassium in DKA

When pH drops, K+ is pumped out of the cell in exchange for H+ because the body is trying to…

10 years ago

WHAT IS THE ANION GAP?

Anion gap = Difference between the unmeasured cations and unmeasured  anions in the serum [artificial] It will done with serum…

10 years ago

Clinical Features of Diabetes

Type 1 Type 2 Abrupt Polyuria (increased urine production) HOW? The increase glucose in the blood will act as an…

10 years ago

Effects of Insulin

Metabolic effects Insulin stimulates Insulin inhibits Carbohydrate metabolism Glucose transport in adipose tissue and muscle Rate of glycolysis in muscle…

10 years ago

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