Hyperprolactinemia: Causes

7 years ago

Prolactin (PRL) is an anterior pituitary hormone which has its principle physiological action in initiation and maintenance of lactation. It…

Myopathy vs. Neuropathy

7 years ago

This is an important clinical distinction to make, but may not always be easy.  Myopathy (Break down or inflammation of…

Rinne vs. Weber: Explained

7 years ago

Rinne and Weber testing are useful clinical bedside assessments to differentiate the two primary causes of hearing loss. RINNE (+):…

Pronator Drift: Mechanism

7 years ago

Pronator Drift is commonly assessed during a stroke assessment. It is a marker of upper motor neuron weakness. MECHANISM: In…

Why does Alpha-1 Antitrypsin Deficiency cause Cirrhosis?

7 years ago

Alpha-1 antitrypsin is an anti protease that protects the lungs from endogenous elastases, collagenases, and protease. These enzymes are responsible for…

What are Pseudo Pelger-Huet cells?

7 years ago

Psuedo Pelger-Huet cells have the morphological characterization of Neutrophils with hypolobation [hypo-segmented]. It can be a benign inherited defect (1/6000)…

Triad of Normal Pressure Hydrocephalus

7 years ago

Classical findings of Normal Pressure Hydrocephalus (NPH) include: Ataxia (typically the initial and most prominent symptom of NPH) Dementia Urinary…

Why Hold Metformin after IV Contrast?

7 years ago

Metformin belongs to the Biguanide class of medications used to treat Type 2 Diabetes. Metformin works by decreasing the amount…

TCA Toxicity and Bicarbonate: Mechanism

7 years ago

Sodium bicarbonate has become the mainstay treatment for arrhythmias caused by TCA toxicity. The cardiotoxic effects of TCA work via…

Compensated vs. Decompensated Cirrhosis

7 years ago

Compensated: Patients with cirrhosis that have not developed major complications of cirrhosis. Decompensated: Patients with cirrhosis who have developed major…

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